Moreover, its handling appears less cumbersome in clinical practice as compared to the latter. The area under the curves (AUC) that predict survival was 0.72 and 0.75 at 3 mo ( P = 0.68), 0.64 and 0.62 at 6 mo ( P = 0.67), 0.69 and 0.64 at 12 mo ( P = 0.38) respectively for the CPT score and the MELD score.ĬONCLUSION: The CPT score displays the same prognostic significance as does the MELD score in black African patients with cirrhosis. Independent factors significantly associated with mortality were: CPT score (HR = 3.3, 95% CI ) ( P 1.5 mg/dL versus serum creatine 21 vs MELD < 21). The overall mortality was 31.4% over 11 years of follow up. Hepatitis B virus infection was the cause of cirrhosis in 70% of the cases. The mean age of the patient was 47.5 ± 13 years. RESULTS: The study population comprised 172 patients, of which 68.9% were male. The Areas Under the Curves were used to compare the performance between scores at 3, 6 and 12 mo. The Kaplan Meier method and the log rank test were used to elaborate and compare survival respectively. Relationship between the two scores was appreciated by calculating the correlation coefficient. METHODS: Univariate and multivariate (Cox model) analyses were used to identify factors related to mortality. AIM: To compare the performance of the Child-Pugh-Turcott (CPT) score to that of the model for end-stage liver disease (MELD) score in predicting survival of a retrospective cohort of 172 Black African patients with cirrhosis on a short and mid-term basis.
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